顱縫是人體頭部用來連接各部位頭骨的組織之ㄧ，由於顱縫具有柔軟性，它可以隨著人體長大將頭部撐開來以形成一個完整的頭形。而顱縫早閉症是一種因為頭部某幾條顱縫過早閉合，限制了頭骨某些方向的成長，造成頭骨及大腦畸形成長的疾病，一般只能經由手術將過早癒合的顱縫切開加以治療，而目前已有人嘗試使用頭套來代替手術進行矯正的動作。本文主要使用二個月大的實驗幼鼠之頭蓋骨配合陰影疊紋法來量測其頭形之三維輪廓，以此結果來建立頭蓋骨與顱縫之ANSYS模型。而後更假設其中某條顱縫發生過早癒合現象時，進行有限元素之應力分析，將結果與醫學上實際之病例比較，結果發現大部分的現象是完全符合的，確定了此方法的可行性。由於國內有關嬰兒頭形的研究尚在起步，本文將可作為研究頭骨模型建立的一個參考。

Sutures are the joints between the bones of skull, a tiny amount of movement is permitted at sutures, which contributes to the compliance of skull. Craniosynostosis is a disease in which some or all of the sutures in the skull of an infant close too early, causing problems with normal growth of brain and/or skull. Craniosynostosis can only be cured with operation, but someone has try to use helmet to adjust this condition. This study uses cranial from 2-month-old mice with shadow Moiré to measure its 3-D profile, and use this result to build ANSYS model, and to simulate the condition of Craniosynostosis with ANSYS. The results are then compared with existed symptom of Craniosynostosis.

中文摘要………………………………………………………………i
Abstract………………………………………………………………ii
目錄…………………………………………………………………iii
表說明………………………………………………………………v
圖說明………………………………………………………………vi

第一章 緒論…………………………………………………1
1.1前言………………………………………………………1
1.2文獻回顧…………………………………………………2
1.3 本文架構…………………………………………………5
第二章 陰影疊紋法與ANSYS簡介…………………………………9
2.1疊紋干涉術……………………………………………9
2.2陰影疊紋法理論簡介……………………………………10
2.3 ANSYS軟體簡介………………………………………13
第三章 實驗規劃及其方法………………………………………20
3.1實驗規劃……………………………………………20
3.2實驗儀器簡介與用途說明……………………………21
3.3光學儀器架設………………………………………23
3.4影像擷取與後續處理…………………………………24
3.5光路驗證…………………………………………25
第四章 頭骨量測與模型建立之結果與討論……………………30
4.1頭蓋骨量測與有限元素模型的建立……………………30
4.2模型之材料性質､邊界條件與負載……………………33
4.3結果討論…………………………………………34
第五章 結論與未來展望………………………………………67
5.1 結論…………………………………………67
5.2 未來展望…………………………………………68
參考文獻………………………………………………71

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