本研究針對科學園區大氣中揮發性有機物、無機酸鹼氣體進行監測，檢視各個揮發性有機物之物種對人體危害程度及大氣污染物在大氣中的分布情況。
周界空氣使用NIEA 715.14B檢測出18種揮發性有機物，濃度較高有丙酮、2-丁酮及甲苯，TVOC為14.32 – 35.09 ppb，其中烷類佔最多52.9%，芳香族29.4%及酮類17.6%，T/B比值14.8 – 18.9，屬於工業區型態。經主成分分析結果可解釋100%變數變異量，因子1命名為半導體廠、移動源，因子2為有機溶劑。
周界空氣無機酸六項檢測物種中，僅測得硫酸 (3.31 – 6.65 μg/Nm3)，低於法規標準50 μg/Nm3，等濃度圖顯示高濃度不在園區內。周界氨氣濃度為0.037 – 0.048 ppm背景濃度較高推測原因為來自附近的水田其次為高科技廠排放，氨氣濃度低於法規標準1 ppm。
揮發性有機物對於人體危害性評估，非致癌風險計算危害指數(HI) 為0.08 – 0.24，皆小於1；而暴露評估條件分有不同肺部吸收率、暴露時間及8小時上班勞工暴露條件，並且使用USEPA IRIS及Cal. EPA (加州環保署)之斜率因子 (slope factor)當作最小及最大值來計算致癌風險。
園區四個監測點VOCs檢測物種中，苯、乙苯及二氯甲烷需要計算致癌風險，以USEPA IRIS之斜率因子計算致癌風險值5.0×10-7至6.05×10-6，以Cal. EPA之斜率因子計算為致癌斜率9.4×10-7至1.0×10-5。計算當地最大風險上班8小時員工之風險，工作10 – 30年，肺部吸收率50 – 70%，即超過可接受致癌風險。

In Houli Central Taiwan Science Park (CTSP), eighteen VOC species, acid gases, and ammonia were measured at four surrounding sites. The concentration of total VOCS, TVOC, was 14.32 – 35.09 ppb, among which alkane was dominant (52.9%), followed by aromatics (29.4%), and carbonyls (17.6). The toluene to benzene ration was 14.8 – 18.9.
Only sulfate acid was detected in the surrounding air, with the concentration of 3.31 – 6.65 μg/Nm3 below the regulation 50 μg/Nm3. The concentration of ammonia (NH3) was 0.037 – 0.24 ppm, contributed mainly by the farmlands, and minor from industrial sources.
Principal component analysis (PCA) identified two factors associated with VOC sources, namely semiconductor processes, mobile sources, gas stations; and organic solvent usage.
The health risks of benzene, ethylbenzene, and dichloromethane were evaluated. Total lifetime cancer risk was 5.0E-07 to 6.0E-06 using USEPA slope factor, and was 9.4E-07 to 1.0E-05 using Cal. EPA slope factor. Also, cancer risk was estimated above 1.0E-06 for an 8-hour worker with 10 – 30 years exposure condition.

摘要..........................................................................................i
ABSTRACT...............................................................................ii
目錄..........................................................................................iii
圖次..........................................................................................v
表次..........................................................................................vii

第一章 前言..........................................................................1
1.1研究源起...............................................................................1
1.2研究目標...............................................................................2
第二章 文獻回顧........................................................................3
2.1后里園區高科技廠之製程.......................................................6
2.2揮發性有機物.......................................................................10
2.2.1揮發性有機物定義及特性...................................................10
2.2.2揮發性有機物來源..............................................................11
2.2.3揮發性有機物危害..............................................................13
2.2.4揮發性有機物風險評估.......................................................18
2.3無機酸鹼.............................................................................20
2.3.1無機酸鹼的來源.................................................................20
2.3.2無機酸鹼危害....................................................................22
2.4影響大氣污染物因子.............................................................23
2.5主成分分析..........................................................................28
第三章 研究方法......................................................................30
3.1研究架構及流程...................................................................30
3.2採樣策略............................................................................31
3.2.1採樣程序及設備................................................................31
3.2.2採樣方法及物種................................................................32
1.空氣中揮發性有機化合物.......................................................32
2.空氣中無機酸類....................................................................35
3.空氣中氨氣..........................................................................38
3.3品保品管............................................................................39
1.實驗室空白(又稱為方法空白分析)...........................................39
2.現場空白..............................................................................39
3.4因子分析/主成分分析...........................................................41
3.5揮發性有機物暴露量評估.....................................................44
3.6致癌風險及非致癌風險評估..................................................47
第四章 結果與討論..................................................................48
4.1揮發性有機物.....................................................................50
4.1.1揮發性有機物濃度............................................................50
4.1.2大氣中揮發性有機物特徵..................................................53
4.2 酸鹼氣體...........................................................................56
4.2.1周界氨氣.........................................................................56
4.2.2周界酸氣.........................................................................59
4.3主成分分析........................................................................61
4.4中部科學園區后里園區VOC健康及致癌風險..........................65
4.4.1非致癌風險評估...............................................................66
4.4.2致癌風險評估..................................................................68
第五章 結論與建議..................................................................81
5.1結論..................................................................................81
5.2建議..................................................................................84
參考文獻................................................................................85
附錄……………………………………………………………………..90

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