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論文名稱 Title |
針對動態四維血流磁共振資料視覺化工具之研製 The implementation of visualization tool for dynamic 4D flow-sensitive MR data |
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系所名稱 Department |
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畢業學年期 Year, semester |
語文別 Language |
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學位類別 Degree |
頁數 Number of pages |
74 |
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研究生 Author |
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指導教授 Advisor |
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召集委員 Convenor |
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口試委員 Advisory Committee |
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口試日期 Date of Exam |
2012-06-08 |
繳交日期 Date of Submission |
2012-06-19 |
關鍵字 Keywords |
4D Flow-sensitive MRI、相位對比、磁振造影、視覺化、血流模式 Phase Contrast, Magnetic Resonance Imaging, 4D Flow-sensitive MRI, Visualization, Blood Flow Pattern |
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統計 Statistics |
本論文已被瀏覽 5667 次,被下載 524 次 The thesis/dissertation has been browsed 5667 times, has been downloaded 524 times. |
中文摘要 |
許多研究與實驗證實:血液流動的模式與心血管疾病是有關聯的,若血液流動時發生異常,是一種心血管疾病的徵兆,而磁振造影(Magnetic Resonance Imaging, MRI)是一種非侵入式的醫學儀器,並利用相位對比(Phase Contrast)的特性可以測量人體內血流的流速與模式。 技術發展至今,已有4D Flow-sensitive MRI,對於感興趣的心血管區域有很好的空間覆蓋範圍與時間解析度並經由視覺化處理,使得研究人員在臨床診斷上更容易分析血液流動的模式。 EnSight (CEI, USA)商業軟體常被用來將4D Flow-sensitive MRI 資料做視覺化處理,但執行視覺化處理前,必須完成幾個前處理,例如:ROI 的圈選、資料的校正與轉換等等。 因此本論文研究希望設計一個簡單且實用的使用者介面工具,將取得的4DFlow-sensitive MRI 資料從讀檔、圈選ROI、資料的校正與轉換到視覺化的呈現,都透過此工具來完成;從結果顯示來看,此工具提供研究人員在診斷上,能夠快速的檢查數據與分析血流模式。 |
Abstract |
Based on many studies and experiments, blood flow patterns are associated with cardiovascular diseases and it usually is a sign of cardiovascular disease when the blood flow becomes unusual. Magnetic resonance (MR) imaging is a non-invasive medical technique and the characteristic of phase contrast can use to measure the flow velocity and patterns in vivo. As far as we know, for the cardiovascular of region of interest, 4D Flow-sensitive MRI technology is good at spatial coverage and temporal resolutions.It is easier for the researcher to analyze blood flow patterns in the clinical diagnosis by visualization processing. EnSight (CEI, USA), a kind of commercial software, is often used to do visualization processing of data of 4D Flow-sensitive MRI. However, before visualization of the data, several actions must be completed, such as ROI selection, correction or conversion of data, and etc. Therefore, our thesis hopes to develop a simple but practical user interface tool for 4D Flow-sensitive MRI data. From reading the file and ROI selection to correction and conversion of data as well as the visualization processing are completed by this tool. It provides researchers a rapid examination of data and analysis of blood flow patterns in the diagnosis. |
目次 Table of Contents |
致謝........................................................................................ i 摘要........................................................................................ ii Abstract ................................................................................ iii 目錄........................................................................................ iv 圖目錄.................................................................................... v 表目錄.................................................................................... vii 第一章 緒論........................................................................... 1 1.1. 概述................................................................................ 1 1.2. 研究動機........................................................................ 2 1.3. 論文架構.........................................................................3 第二章 文獻探討................................................................... 4 2.1. 磁振造影........................................................................ 4 2.2. 心臟磁振造影................................................................ 8 2.3. 相位對比磁振影像........................................................ 9 2.4. 心電圖與呼吸監控........................................................ 12 第三章 研究方法與步驟....................................................... 13 3.1. 資料收集........................................................................ 13 3.2. 研究方法........................................................................ 17 3.2.1. GUI 介面與流程步驟 ................................................ 17 第四章 結果與討論............................................................... 38 第五章 結論........................................................................... 43 第六章 參考文獻................................................................... 44 附錄 A 完整結果.................................................................... 47 附錄 B 使用手冊.................................................................... 57 |
參考文獻 References |
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