本論文利用金金屬作為催化試劑，及銀金屬催化試劑活化金金屬催化試劑之特性，或利用其他輔助催化試劑活化金金屬試劑，在不同溶媒中，加熱至迴流溫度，對4-甲氧基芐基-2-（苯基乙炔基）苯甲酸甲酯及其衍生物進行催化環化反應，形成環化產物具有異香豆素結構之化合物，以及形成環化轉位之產物4- （4-甲氧基芐基）-3-苯基-1H-異色烯-1-酮。

In this research, a new method was discovered to selectively obtain cyclic product under gold catalyst and silver co-catalyst or other co-catalyst. Using
4-methoxybenzyl 2-(phenylethynyl)benzoate and their deriviatives under gold and co-catalyst catalyzed in different solvent at 80 oC to get cyclic product 3-phenyl-1H-isochromen-1-one (isocoumarin), and the 4-(4-methoxybenzyl)-3-phenyl-1H-isochromen-1-one also can be obtain in the same time.

審定書 i
致謝 ii
摘要 iii
Abstract iv
圖目錄 vi
表目錄 vii
1-1金金屬催化試劑簡介 1
1-2金金屬催化試劑之使用 3
1-2-1 過度金屬催化稀缺類反應 3
1-2-2 金金屬催化稀缺類反應 5
1-2-3 金金屬催化重排反應 6
1-3異香豆素化合物之合成及應用 9
1-3-1異香豆素化合物及衍生物之應用 9
1-3-2異香豆素及衍生物之合成 12
1-4 實驗室文獻回顧 18
第二章 25
2-1研究動機 25
2-2結果與討論 25
2-3 結論 39
第三章 文獻參考 41
第四章 實驗部分 44
4-1 實驗儀器 44
4-2試藥部分 45
第五章 附錄 46
5-1實驗步驟 46
5-2 光譜數據與物理性質 48
5-3 X-ray 單晶繞射數據 86
第六章、光譜附圖 1

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