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博碩士論文 etd-0706115-164259 詳細資訊
Title page for etd-0706115-164259
論文名稱
Title
金屬玻璃薄膜濺鍍在光學玻璃上之抗菌以及抗黴菌效果
Antibacterial and Antifungal Effects of Thin Film Metallic Glasses Deposited on Optical Glass
系所名稱
Department
畢業學年期
Year, semester
語文別
Language
學位類別
Degree
頁數
Number of pages
139
研究生
Author
指導教授
Advisor
召集委員
Convenor
口試委員
Advisory Committee
口試日期
Date of Exam
2015-07-21
繳交日期
Date of Submission
2015-08-06
關鍵字
Keywords
抗黴菌、抗菌、金屬玻璃、光學材料、黑麴黴
Al-Ni-Y, Aspergillus niger, antibacterial, metallic glasses, antifungal
統計
Statistics
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The thesis/dissertation has been browsed 5677 times, has been downloaded 95 times.
中文摘要
在近年來的研究,金屬玻璃的應用越來越廣,因為金屬玻璃擁有許多優良的特性,像是優良的機械性質、良好的抗磨耗、抗腐蝕性的能力以及熱穩定性。現今的金屬玻璃薄膜製作工法日趨容易,在工業上的應用也越來越廣,像是生醫材料、光學材料及微機電系統上面。
但是關於金屬玻璃薄膜在抗菌的領域上面,相對而言研究的就少了很多。銀和鋁已經在很多研究上證明其擁有良好的抗菌效果,尤其是銀。而鋁的缺點也比較明顯,像是對生物毒性較高還有容易使離子釋出崩解,但鋁作為反射膜是良好的材料。
主要研究Al-Ni-Y金屬玻璃薄膜作為抗菌的效果,以調整Al的含量不同來研究其反射性以及抗菌效果之間的關係。首先在光學玻璃上面鍍上Al68Ni18Y14、Al72Ni16Y12及 Al76Ni14Y10三種成分的薄膜,接著去測試電阻值以及反射率,最後再去做抗菌的研究。
抗菌的細菌挑選為大腸桿菌以及金黃色葡萄球菌,分別為革蘭式陰性菌和革蘭氏陽性菌,都是日常生活中常見的細菌。抗黴菌的黴菌選擇上為黑麴黴和皺褶青黴及出芽短梗黴,皆為日常中生長在光學玻璃或儀器上的黴菌。
Abstract
Many studies show that the metallic glasses exhibit better properties, such as high strength, hardness, corrosion resistance, larger elastic energy storage and electrical or magnetic. Nowadays, it is more easily to fabricate the thin film metallic glasses, which have been used widely in industry, such as optical film, biomaterial or micro-electro-mechanical-system (MEMS).
There are few applications of metallic glasses for antimicrobial properties. Moreover, the metallic thin films with high reflection, such as silver and aluminum, show the good antimicrobial property, especially silver. The weak point of aluminum is also obvious, such as the higher toxicity and the ion release easily, but aluminum as reflective film is good material.
In this study, it is thus researching the anti-fungal and anti-bacterial activity of Al-Ni-Y metallic glass thin films, to adjust the different Al content to discuss the relationship between reflective and antibacterial activity. First, to synthesize Al-Ni-Y TFMGs on the optical glass with different compositions of Al, then test the resistance and reflectivity, finally do the antibacterial test.
E. coli and S. aureus, who were Gram-negative bacteria type and Gram-positive bacteria, were chosen to do the antibacterial test, because they are the common bacteria in life. Aspergillus niger, Penicillium rugulosum and Aureobasidium pullulans were chosen to do the antifungal test, because they are growing on the optical glass and instrument.
目次 Table of Contents
論文審定書 i
致謝 ii
中文摘要 iv
Abstract v
Content vi
List of tables x
List of figures xii

Chapter 1 Introduction 1
1-1 Amorphous alloys 1
1-2 The development of thin film metallic glasses 1
1-3 Optical thin films 2
1-4 Motivation 3
Chapter 2 Background and literature review 5
2-1 The behavior of amorphous alloys 5
2-1-1 Mechanical properties 5
2-1-2 Corrosion properties 5
2-2 Empirical rules for synthesis of metallic glasses 6
2-3 Thin film metallic glasses (TFMGs) 7
2-4 Principle of physical vapor deposition (PVD) 7
2-4-1 Introduction of sputtering process 8
2-4-2 DC/RF magnetic sputtering process 10
2-4-3 Growth of sputter-deposited thin film 12
2-5 Principles of optics 13
2-5-1 Light reflection 13
2-5-2 Light refraction 14
2-5-3 Correlation of resistivity and reflectivity 15
2-5-4 Optical properties of metallic glasses 16
2-6 Antimicrobial activity 17
Chapter 3 Experimental procedures 20
3-1 Raw materials 20
3-2 Sample preparation 20
3-2-1 Pretreatment for substrate 21
3-2-2 Thin film preparation 21
3-3 Property measurements and analyses 22
3-3-1 X-ray diffraction 22
3-3-2 SEM observations 22
3-3-3 Qualitative and quantitative component analyses 23
3-3-4 3D alpha-step profilometer 23
3-3-5 Atomic force microscopy 24
3-4 Optical reflection properties 24
3-4-1 n&k analyzer 24
3-4-2 Four-point probe 24
3-5 Biological assay 25
3-5-1 Antibacterial test 25
3-5-2 Antifungal test 26
3-6 Inductively couples plasma-mass spectrometry 27
Chapter 4 Results and discussion 28
4-1 Preparation of thin films metallic glasses 28
4-2 The Al-Ni-Y and the Al-Ni-Y-Ag thin films 29
4-2-1 XRD analysis 29
4-2-2 SEM EDS observations and measurements 30
4-2-3 Optical and electric resistivity analysis 31
4-3 Rapid thermal annealing 32
4-3-1 XRD analysis 33
4-3-2 SEM EDS observations 33
4-3-3 Optical and electric resistivity analysis 34
4-4 The relationship of electric resistivity and reflectivity 35
4-5 Morphology analysis 36
4-6 Antibacterial test 37
4-7 Antifungal test 38
4-7 After antimicrobial testing 39
4-7-1 XRD analysis 40
4-7-2 SEM EDS observations 40
4-7-3 Optical analysis 41
Chapter 5 Conclusion 42
Tables 49
Figures 60
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