由於人們對於睡眠品質漸漸重視，故對睡眠呼吸中止症診斷得需求提高，但因睡眠呼吸中止症的診斷不便且昂貴，故發展一套簡易的自我檢測十分重要。由於rRR值能反應心律穩定性，利用此特性提出了一系列的特徵廋數希望能用來評估RDI的嚴重程度。
最後再看各特徵變數之間是否有一定程度的獨立性，以期望能同時將不同的特徵變數來評估RDI。最後再以年齡、BMI及男女分類不同族種來看各特徵變數與RDI之間的相關性。

Because people pay attention to sleep quality gradually, So the demand for diagnosing sleep apnea syndrome improves, but because it is inconvenient and expensive to diagnose sleep apnea syndrome, so it is very important to develop a set of simple and easy self- measuring. Because rRR valu can response heart rate stability, using this property to advance a series of feature parameter hope to estimate RDI
Final research the relationship between every feature parameters , because we hope be able to use different feature parameters to estimate RDI. At last research the relationship between DRI and feature parameters by classing with age, BMI, men and women.

論文目錄I
圖表目錄III
摘要(中文)VI
摘要(英文)VII
第一章 緒論1
1.1前言1
1.2研究動機3
1.3論文架構4
第二章 睡眠狀態與睡眠呼吸障礙指數相關性5
2.1睡眠狀態5
2.1.1睡眠狀態的檢測5
2.2睡眠呼吸障礙指數6
2.3各睡眠狀態與RDI6
第三章 rRR值與睡眠狀態相關性12
3.1前言12
3.2 rRR值的定義12
3.3不同睡眠狀態下的rRR值13
3.4 rRR值與RDI的相關性14
第四章rRR值特徵變數群與RDI的相關性17
4.1前言17
4.2 時域的rRR值特徵變數群與RDI的相關性17
4.3頻域的rRR值特徵變數群與RDI的相關性19
4.3.1前言19
4.3.2搜尋特定頻帶能量和RDI的相關性19
4.3.3搜尋正規化後特定頻帶能量和RDI的性20
4.3.4正規化rRR值視窗的特定頻帶能量和RDI的 相關性26
4.4各特徵變數的比較28
4.5特徵變數群與不同族群病歷比較33
第五章 結論41
參考文獻43

Bootsma, M., C. A. Swenne, H. H. Van Bolhuis, P. C. Chang, V. M. Cats, and A. V. G. Bruschke. “Heart rate and heart rate variability as indexes of sympathovagal balance.” Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1565–H1571, 1994.

Bonnet, M. H., and D. L. Arand. “Heart rate variability: sleep stage, time of night and arousal influences. ” Electroencephalogr. Clin. Neurophysiol. 102: 390–396, 1997.

Helen Otzenberger, CLaude Gronfier, Chaantal Simon, Anne Charlux,Jean Ehrhart, Francois piquard, And Gabrielle Brandenberger,1998,“Dynamic heart rate variability: a tool for exploring sympathovagal balance continuously during sleep in men” the American Physiological Society

Pivik, R. T., K. A. Busby, E. Gill, P. Hunter, and R. “Nevins. Heart, autonomic nervous system, and sleep. Heart rate variations during sleep in preadolescents. ”Sleep 19: 117–135, 1996.

Schechtman, V. L., R. K. Harper, and R. M. Harper. “ Development of heart rate dynamics during sleep-waking states in normal infants. ” Pediatr. Res. 34: 618–623, 1993.





Stein, K. M., N. Lippman, and B. B. Lerman. “Heart ratevariability and cardiovascular risk assessment. In: Hypertension: Pathophysiology, Diagnosis and Management, ” edited by J. H. Laragh, and B. M. Brenner. New York: Raven, 1995, p. 889–903.