在數十年前，電刺激已被應用在四肢癱瘓或下半身癱瘓病人的復健上，如走路，站立，與周期性的練習上。隨著近年來超大型積體電路的發展，可植入式之微電刺激系統已成為可實現的目標。此篇論文提出一完全植入的系統，其中包括使用線圈互感傳遞功率與資料，通訊協定與封包，與功能性電刺激系統單晶片之實現方式。
此論文的第一部分探討完全植入式功能性電刺激系統之架構，包括無線功率傳輸之理論，類比與數位電路之混合訊號實現方式，RS232通訊協定，與兩種資料編碼 – 曼徹斯特編碼與NRZ編碼。論文的第二部分討論多種頻率刺激之可植入式功能性電刺激系統版本，論述主要集中於適合多種頻率刺激功能之通訊協定，與改良式的晶片訊號連結方式上。

For several decades of years, the electrical stimulation has been applied on rehabilitation of motional recovery for quadriplegic and paraplegic patients such as walking, standing, and cycling exercise. As the advancement of VLSI (very large scale integration) technology, the implantable micro-stimulators become feasible in recent years. This thesis presents an implantable system including an inductively coupling transceiver of power & data, a protocol of communication, and the implementation of a FES (Functional Electrical Stimulation ) SOC (System-On-chip).
The first part of this thesis discusses the architecture of the proposed implantable FES system, including the theory of wireless power transmission, the implementation of mixed-signal circuits, the RS232 protocol, and two encoding methods of Manchester code and NRZ code.
The second part of this thesis is focused on the multi-frequency stimulation of the implantable FES system, which comprises an advanced communication protocol suitable for multi-frequency stimulation function and a novel arrangement of interconnections for the chip.

摘要 i
Abstract ii
第一章 簡介 1
1.1 背景 1
1.2 植入式功能性電刺激系統介紹 2
1.3 完全植入式功能性電刺激系統技術簡介 3
1.4 研究動機 5
1.5 論文大綱 5
第二章 植入式功能性電刺激系統 7
2.1 系統架構與規劃 7
2.2 無線功率傳輸系統 9
2.2.1 簡介 9
2.2.2 線圈感應 10
2.2.3 E類功率放大器 13
2.3 類比與混合訊號電路 17
2.3.1 穩壓器 17
2.3.2 ASK解調器 19
2.3.3 5 MHz 時脈產生器 21
2.3.4 電源起始重置訊號產生器 22
2.3.5 雙向電流式數位類比轉換器 25
2.4 通訊協定 27
2.4.1 曼徹斯特編碼通訊協定 27
2.4.2 RS232簡介 29
2.4.3 NRZ編碼通訊協定與架構 30
2.4.3.1 通訊協定 30
2.4.3.2 數位控制電路 33
2.5 模擬結果 36
2.6 量試結果 42
2.6.1 數位部分量測結果 42
2.6.2 類比部分量測結果 44
2.7 討論 45
第三章 多種頻率電刺激之功能性植入式單晶片 47
3.1 簡介 47
3.2 系統架構 47
3.3 類比與混合訊號電路 49
3.3.1 PAD實現 49
3.3.2 具有溫度補償之時脈產生電路 51
3.4 通訊協定 53
3.5 模擬結果 57
第四章 結論與展望 60
參考文獻 61

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