| URN |
etd-0717102-154451 |
| Author |
Chien-Cheng Chen |
| Author's Email Address |
No Public. |
| Statistics |
This thesis had been viewed 4567 times. Download 1799 times. |
| Department |
Physics |
| Year |
2001 |
| Semester |
2 |
| Degree |
Master |
| Type of Document |
|
| Language |
zh-TW.Big5 Chinese |
| Title |
Using Simulated Annealing Method to Resolve the Structure of Myoglobin |
| Date of Defense |
2002-06-28 |
| Page Count |
50 |
| Keyword |
simulated annealing
protein
α-helix
Myoglobin
|
| Abstract |
The α-helix structure of protein is very similar to the cylindrical structure. Especially, the Sperm-Whale Myoglobin molecules has 70% α-helix structure. Therefore, we use simulated annealing method to solve “X-ray phase problem”, and apply Metropolis algorithm to avoid local minimum. We hope that the new method can build α-helix structure of Sperm-Whale Myoglobin molecule. Therefore, we use multi cylinders as the Myoglobin’s tertiary structure and solve the cylinder’s structure with the simulated annealing method. |
| Advisory Committee |
Chiang Michael Yen-Nan - chair
Herng-Yih Ueng - co-chair
Wang-Chuang Kuo - advisor
|
| Files |
indicate accessible in a year |
| Date of Submission |
2002-07-17 |