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博碩士論文 etd-0727110-104244 詳細資訊
Title page for etd-0727110-104244
論文名稱
Title
針對相位陣列線圈的氫質子磁振頻譜合併前與合併後做渦電流校正之量化分析比較
The quantitative comparison of doing eddy current correction before and after combination for 1H MRS using phased array coils with LCModel
系所名稱
Department
畢業學年期
Year, semester
語文別
Language
學位類別
Degree
頁數
Number of pages
58
研究生
Author
指導教授
Advisor
召集委員
Convenor
口試委員
Advisory Committee
口試日期
Date of Exam
2010-06-28
繳交日期
Date of Submission
2010-07-27
關鍵字
Keywords
LCModel、磁振頻譜、渦電流、相位陣列線圈
Phased Array Coils, Eddy Current, Magnetic Resonance Spectroscopy, LCModel
統計
Statistics
本論文已被瀏覽 5630 次,被下載 2
The thesis/dissertation has been browsed 5630 times, has been downloaded 2 times.
中文摘要
相位陣列線圈是由一組相互分離的表面線圈所組成,能同時接收個別的線圈信號,個別的表面線圈能提供相當於線圈直徑範圍內較高的信雜比。因此,結合這些非交互的個別線圈所組成的相位陣列線圈,可以獲得到一個大範圍的掃描區域,並且有均勻的靈敏度與較佳信雜比。

我們的研究將針對個別線圈做渦電流校正以及合併之後在做渦電流校正的不同,利用LCModel分析後得到的代謝物濃度定量結果,驗證各別表面線圈做渦電流校正後,所得到相位陣列線圈的磁振頻譜資料的結合,在活體上磁振頻譜的信雜比和絕對濃度的可靠度與準確性。

因此實驗分別使用正交線圈 (quadrature coil) 與相位陣列兩種不同線圈,相位陣列線圈磁振頻譜資料不同結合方式的比較,利用正交線圈為控制組,用來驗證代謝物濃度的可靠度與準確性。我們的結果顯示,對每個相位陣列線圈在信號合併前做渦電流校正,對信雜比和活體上的磁振頻譜的定量濃度可以得到優良的可靠性和準確性。
Abstract
Phased array coils are composed of several surface coils receiving individual element signals simultaneously. Each individual surface coil provides the equivalent of the coil diameter range, and higher SNR. Therefore, combining these non-interactive phased array coils, can achieve a wide range of scan areas, uniform sensitivity and better SNR.

Therefore our experiment was performed with two different coils of quadrature coil and phased array coil. Phased array MRS data were compared using various combination approaches. Data acquired by quadrature coil was regarded as a standard to verify the reliability and accuracy of metabolite concentration.

The aim of our study is to do eddy current correction before and after the combination of each element coil data with LCModel analysis for quantitative comparison of metabolite concentrations. Our result shows that doing eddy current correction for each phased array coil before signal combination can achieve higher reliability and accuracy of SNR and quantitative concentrations of MR spectra in vivo.
目次 Table of Contents
致謝 i
中文摘要 ii
Abstract iii
圖目錄 vi
表目錄 viii
第一章 導論 1
第一節 前言 1
第二節 文獻回顧 4
第三節 動機 7
第四節 大綱 8
第二章 工具與方法 12
第一節 磁振頻譜取得方式 12
壹、 正交線圈(Quadrature coil) 12
貳、 相位陣列線圈(Phased Array Coils) 14
第二節 磁振頻譜檔案的分析 15
壹、 LCModel 15
貳、 Web-tool 16
參、 相位陣列線圈的磁振頻譜信號合併 17
肆、 渦電流校正(Eddy current correction) 17
第三節 定量分析後結果比較 20
壹、 信雜比(SNR) 20
貳、 代謝物濃度的比較 22
第四節 實驗設計 22
第三章 實驗結果 32
第一節 信雜比結果的比較 33
第二節 定量分析後代謝物絕對濃度的比較 34
第四章 結論 47
第五章 參考文獻 48

參考文獻 References
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