本論文提出一個適用於可攜式生理訊號記錄系統的低功率電流式儀表放大器。此放大器主要作為生理訊號記錄系統的前端放大器。一般來說，生理訊號是相當微弱的，例如心電圖。所以需要一個具有適當放大增益的前端放大器來做訊號的放大，以利系統後端的運作分析。而低功率的特性將可使系統的運作時間有顯著的延長。
整個設計流程從原理的了解、電路設計與模擬、實體佈局與測試結果，在本論文中皆有詳述。此外也提出一個生理訊號記錄系統的原型以及其他相關軟硬體加以模擬實作，並呈現其量測結果。本論文所提出的低功率儀表放大器是在TSMC 0.35 μm 2P4M CMOS製程下所完成。

In this thesis, a low-power current-mode instrumentation amplifier is proposed for the portable physiological signal recording system. This proposed instrumentation amplifier is used as a front-end amplifier of physiological signal recording system. In general, the physiological signal is very small, for example, the electrocardiogram (ECG) signals. Therefore, the system needs a front-end amplifier to amplify small physiological signals so that it is easier to analyze the signals. Besides, the system will be operated for a longer period because of the proposed amplifier’s low-power property.

The circuit theorem, design process and simulation, circuit layout as well as the measurement results all have detailed description in this study. Moreover, a specific physiological signal recording system prototype is proposed. This proposed instrumentation amplifier has used TSMC 0.35 μm 2P4M CMOS process technology.

Abstract
Chapter 1 Introduction 1
1.1 General Background Information 1
1.2 Electrocardiogram (ECG) 2
1.3 Basic Instrumentation Amplifier 3
1.4 Design of the Proposed Physiological Signal Recording System 5
1.5 Contribution of This Thesis 6

Chapter 2 Proposed Physiological Signal Recording System 7
2.1 Basic Concept 7
2.2 The Prototype of Physiological Signal Recording System 9
2.3 Simulation Result of the Prototype System 17

Chapter 3 Low Power Instrumentation Amplifier for Portable Recording 20
3.1 Basic Concept and Basic Instrumentation Amplifier 20
3.2 Circuit Description of Proposed Instrumentation Amplifier 22
3.2.1 Main Circuit 22
3.2.2 Current Mirror 22
3.2.3 Common Mode Feedback 32
3.2.4 Instrumentation Amplifier for Sampled System 34

Chapter 4 Simulation Results and Layout 38
4.1 Simulation of Proposed Instrumentation Amplifier 38
4.1.1 Simulation Results 38
4.1.2 Monte-Carlo and Corner Simulation 42
4.2 Layout of Proposed Instrumentation Amplifier 44
4.2.1 Resistor 44
4.2.2 Capacitor 46
4.2.3 The Layout of Whole Circuit 47

Chapter 5 Measurements Result 49

Chapter 6 Conclusion 54

Reference 55
Appendix A 56
Appendix B 60
List of Publications 63

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