華南鼬鼠（Mustela sibirica）為廣布於歐亞大陸的食肉目動物。臺灣的華南鼬鼠棲息於多樣的環境之中，但分布多侷限於海拔八百公尺以上的山區。本研究利用華南鼬鼠的粒線體控制區域序列，分析其在臺灣的地理親緣變異及基因交流情形。結果得知，華南鼬鼠的粒線體控制區域序列平均長度為1038.9 bp，結構上可分為ETAS、CD及CSB三大區域，位於中間的CD區變化最少，而其兩邊的區域變化較多。在CSB區域中則有常見於其他食肉目動物的反覆重複片段。親緣關係方面，由各親緣關係樹及MSN圖均可得到三個主要的系群。系群的分布與地理位置大致相關，系群I主要分布於臺灣南部；系群II及III則主要分布於臺灣北部。雖然每各系群間的基因交流程度很低，但是在系群的分布上卻不見有明顯的地理隔離障礙，推測這些分離的系群可能和臺灣其他的高海拔哺乳動物一樣，主要為瓶頸效應所造成的結果，而非地理的隔離所致。

Siberian weasel, Mustela sibirica is a widespread carnivora mammal in Eurasia. In Taiwan, it inhabits a variety of environments restricted to altitude above 800 m. Based on mitochondrial control region sequences, I constructed phylogeography and analyzed population interflow about the species in Taiwan. The mean length of D-loop in Siberian weasel is 1038.9 bp. The D-loop structure can be divided into ETAS, CD and CSB domain. Among these, CD is the most conserved region while the two flank domains are variable. There are tandem repeat sequences in CSB domain, common in other carnivores. In phylogenetic analyses, three major lineages were found in phylogenetic trees and MSN topology. In general, haplotypes in clades are correlated to geographic distribution. The haplotypes of clade I were sampled from southern Taiwan, while the majority of those clade II and clade III were from northern Taiwan. The gene flow among clades were low. However no significant geographic boundaries existed between clades. It is speculated that the genetic isolation among clades may have been resulted from bottleneck effect, like other high altitude mammals in Taiwan, and not from geographic barriers mainly.

Chinese abstract………………………...………………........I
English abstract…………………………………………........II
Introduction……………………………………………….........1
Material and Methods…………………………………...……....4
Results…………………………………………………...……....12
Discussion…………………………………………………..…....16
References………………………………………………….….....20
Figures……………………………………………………….......25
Tables…………………………………………………………......33
Appendix………………………………………..……………......43

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